ZERONA™
ZERONA™ The first non-invasive body contouring procedure to effectively remove excess fat.
Unlike invasive weight loss surgery, ZERONA™ is applied externally. This revolutionary method provides results without the dangers associated with surgery,
while at the same time allowing patients to remain active during treatment. The ZERONA™ protocol utilizes the Erchonia® Laser Scanner, the safest and most
researched low level laser in the world.
How ZERONA™ Works
Voluminous adipose tissue can appear when fatty material is present, and this, in turn, can bring about enlarged subcutaneous fat regions. Because subcutaneous
fat is close to the skin's surface, laser emulsification can have a dramatic effect. The collapse of adipose arrangements have been noted after laser therapy,
reducing their volume and providing effective body contouring results.
Process Overview
Erchonia® Laser Scanner Biochemical Effects on Adipose Tissue

The stunning series of photographs above impressively demonstrates the low level laser’s ability to emulsify adipose tissue. The pictures show the collapse of the rigid adipose cell and the secretion of triglycerides and fatty acids. These remarkable images immediately reveal why laser-assisted liposuction can serve as a great benefit for the physician and the patient.
Why do Triglycerides and Fatty Acids Seep Across the Membrane?

These images reveal the formation of a transitory pore forming in the bi-lipid membrane of an adipose cell. This pore formation is the direct result of laser stimulation, and the reason why the triglycerides and fatty acids move into interstitial space. The pore is not damaging to the cell, but simply serves as a means for the fatty contents of the cell to evacuate. The formation of the transitory pore is the product of a series of secondary reactions originating in the mitochondria.
How does low level laser treatment affect cells?
I will begin to walk you through a series of primary and secondary reactions that originate in the mitochondria of a single cell and can migrate throughout the whole body!
The mitochondrion is an energy station for all eukaryotic cells, and that energy produced in the mitochondrion is what provides life to the entire organism. The mitochondrion is where adenosine tri-phosphate (ATP) is produced, an essential molecule driving many reactions.
The mitochondrion is the specific target for Erchonia® low level laser devices. Specifically, cytochrome c oxidase, a terminal enzyme, is targeted by the low level laser. Cytochrome c oxidase is a photoacceptor, absorbing light at a peak spectrum of 630-670 nm (red spectrum). This particular molecule is responsible for ensuring that the Respiratory Chain goes to completion. The Respiratory Chain harvests electrons from O2 and NADH passing them along through a series of redox reactions, ultimately producing ATP and H2O. Cytochrome c oxidase promotes the electron flow along the Respiratory Chain between Complexes III and IV.
Low level laser is proposed, based on a study performed in 2005, to stimulate photoexcitation of certain reaction centers in the cytochrome c oxidase molecule (like CuA and CuB) influencing the redox state of these molecules, and consequently, the rate of the electron flow in the molecule; meaning, photoexcitation of cytochrome c oxidase may lead to redox changes and modulations of biochemical reactions through a cascade of reactions called photosignal transduction (stimulation of other reactions).
Product Overview
The Erchonia® Laser Scanner is specially designed for use during liposuction and the ZERONA™ non-invasive body contouring procedure. The laser is applied externally and has proven through double blind clinical trials to emulsify adipose tissue.
Whether you are doing a traditional liposuction procedure or the new ZERONA™ protocol by Erchonia®, you can be confident you are giving your patients the safest and most researched low level laser in the world.
Patient Frequently Asked Questions
1. How does it work?
A. Through clinical studies it has been demonstrated that the Zerona low-level laser stimulates
the fat cell to emulsify (liquefy) the fat within the cell. Then the liquefied fat moves from
inside the cell through a temporary pore formed in the cell membrane to outside the cell
where it is in the interstitial space until absorbed by the lymphatic system. This results in
millions of fat cells becoming smaller so inches are reduced off the waist, hips and thighs.
The fat cells are not injured in any way by this process.
2. What can I expect at my appointments?
A. You can expect 40 minutes to relax, read or do absolutely nothing. The Zerona treatment is
completely painless. There is no heat or any sensation whatsoever while being treated.
Each treatment you will be met by your physician or technician who will position the laser at
the desired areas of the body, he/she will step out for 20 minutes while the front of your
body is treated and then will return to reset for the backside of your body for an additional 20
minutes. After you are done you can get back to your normal activities immediately with
absolutely no downtime, nor pain, swelling or any discomfort. This is a symptom –free
process except for losing unwanted inches.
3. What happens if I miss an appointment?
A. It is not recommended that you miss an appointment. Prior to starting the Zerona treatment,
it is important that you are committed to the recommended lifestyle protocol which includes 6
treatments, every other day for 40 minutes and not to exceed 72 hours between treatments.
If more than 72 hours passes between appointments, some of the fat may be reabsorbed by
the fat cells.
4. How is it different than liposuction?
A. Liposuction is an invasive procedure that removes the entire area of fat cells from deposits
beneath the skin using a hollow stainless steel tube (called a cannula) with the assistance of
a powerful vacuum. Liposuction can be accomplished either with the use of general
anesthesia, or with IV sedation, or totally by local anesthesia. In contrast, the Zerona
treatment is a 100% non-invasive that uses a low level laser applied externally to stimulate
the fat cell and emulsify and release fat. There is no use of anesthesia, nor any pain, gels,
creams, numbing agents, needles and no downtime.
5. Is there any downtime?
A. Absolutely ZERO downtime. During the treatment you will feel no discomfort, no anesthesia
will be used and you can assume normal activities immediately following each treatment.
6. Are there any limitations to what I can do if I’m using Zerona?
A. No. During the 2 week treatment period you can continue your normal activities. It is strongly
recommended that you commit to and follow the treatment protocol: stay hydrated (8-10
glasses of water a day), continue to eat healthy and exercise (walk at least 30 minutes a
day), and abstain from alcohol and caffeine. Alcohol and caffeine interfere with the lymphatic
process to metabolize it fat which can decrease your results.
7. What areas of the body can I use Zerona on?
A. The Zerona treatment can be used effectively on essentially every part of the body where
localized fat deposits exist that are resistant to diet and exercise. Most patients start with
treating the waist, hips and thighs which can all be targeted in 1 treatment. Other areas
include upper arms, bra-line fat, inner knees, back fat and buttocks.
8. Is it covered by insurance?
A. No, Zerona treatments are considered elective and are not covered by insurance.
9. Is it safe?
A. Yes, there is no risk involved in using the Zerona low-level laser therapy and it is considered
a safe alternative to invasive procedures such as tumescent liposuction and lipodissolve and
other non-invasive devices like the Accent, VelaShape, and Thermage ,which rely on
heating the tissue and can cause discomfort. None of these have the proven data showing
how fat cell size is reduced like the Zerona. The Zerona treatment is 100% non-invasive and
causes no bruising, scarring and zero downtime. During the treatment you will feel no
discomfort, no anesthesia will be used and you can assume normal activities immediately
following each treatment.
10. Is it safe if I have a medical condition such as diabetes?
A. Yes, with two exceptions. If you are pregnant or think you may be pregnant, Zerona should
not be used. Additionally, if you have a pacemaker, this treatment may not be for you.
There are no known detrimental risks but potential unknown risks may exist. Zerona may not
be as effective on patients with diabetes or thyroid disorders where the metabolic system is
potentially impaired. Please consult with your doctor to discuss whether you are a good
candidate for Zerona treatments based on your medical history.
11. Are there any side affects?
A. No. The treatment process is completely non-invasive and there are absolutely no side
effects beyond loss of inches and fat.
12. How long has the Zerona laser been used?
A. The Zerona has been used in studies since 2008 and has been used by physicians in
practice since early 2009. The same Erchonia Low Level Laser technology has been used
to safely assist with tumescent liposuction since 2001 and was established as a proven
method to release fat cells immediately prior to liposuction surgery. Low Level Lasers have
been in use for over 40 years for treatment of many different conditions such as chronic
pain, would healing, and many other orthopedic conditions.
13. Is it effective?
A. Yes, with the Zerona treatment and by following the recommended guidelines for success,
you can expect to experience a combined loss of 3 – 9 inches from your waist, hips and
thighs and a reduction in clothes size. Additionally, early patients have noticed an
improvement in the appearance of cellulite.
14. How long do results last?
A. By maintaining a healthy diet and exercise you can expect long-term results. Zerona is
especially ideal for 2 types of people: those that are already following a healthy diet and
lifestyle and want to remove localized pockets of fat OR those who want to use the Zerona
and the recommended lifestyle protocol to “jump start” their slimming efforts as motivation
for maintaining a healthier and slimmer lifestyle.
15. Can I do the procedure multiple times? And how soon after my last treatment can I do a second
treatment?
A. Yes, with additional treatments you can expect to see improved results. You can start an
additional series of Zerona treatments immediately following your last treatment.
16. How soon after pregnancy can I do it?
A. It is recommended that you wait until after your last postpartum visit with your doctor (usually
6 weeks after birth) to begin your Zerona treatment. It is not recommended if you are breast
feeding.
17. How long does it take to begin seeing results?
A. Some can see results after only a few treatment sessions as their clothes fit more loosely.
Many actually see the difference after 4-6 sessions. Family and friends often notice the
difference, too, within the 2 week Zerona program.
18. Is everyone a good candidate for the Zerona treatment?
A. Most are good candidates. Even people who are not overweight can lose inches. Be sure to
discuss your health background with your physician and ask any questions about your
particular areas of concern.
For ZERONA™ non-invasive body contouring in Thousand Oaks or Oxnard California contact Dr. David Michelson
Thousand Oaks office:
223 East Thousand Oaks Boulevard,
Suite 211
Thousand Oaks, CA 91360
(805) 495-6411;
toll-free: 1 (800) 643-6355
fax: 805-495-0641 |
Oxnard office:
200 South A Street,
Suite 300
Oxnard, CA 93030
(805) 486-1966;
toll-free: 1 (877) 212-4111
fax: 805-495-0641 |
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